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Cerebrospinal fluid abnormalities in a phase III trial of Avonex® (IFNβ-1a) for relapsing multiple sclerosis

✍ Scribed by Richard A. Rudick; Diane L. Cookfair; Nancy A. Simonian; Richard M. Ransohoff; John R. Richert; Lawrence D. Jacobs; Robert M. Herndon; Andres M. Salazar; Jill S. Fischer; Carl V. Granger; Donald E. Goodkin; Jack H. Simon; David M. Bartoszak; Dennis N. Bourdette; Jonathan Braiman; Carol M. Brownscheidle; Michael E. Coats; Stanley L. Cohan; David S. Dougherty; Revere P. Kinkel; Michele K. Mass; Frederick E. Munchsauer; Kathy O'Reilly; Roger L. Priore; Patrick M. Pullicino; Barbara J. Scherokman; Karl Wende; Bianca Weinstock-Guttman; Ruth H. Whitham


Book ID
114138252
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
174 KB
Volume
93
Category
Article
ISSN
0165-5728

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✍ Maria A. Rocca; Federica Agosta; Bruno Colombo; Domenico M. Mezzapesa; Andrea Fa 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 228 KB

## Abstract If fatigue in multiple sclerosis (MS) is related to an abnormal activation of the sensorimotor brain network, the activity of such a network should vary with varying fatigue. We studied 22 patients treated with interferon beta 1a (IFNβ‐1a; Avonex, Biogen, Cambridge, MA) with no fatigue