Magnetic resonance studies of intramuscular interferon β–1a for relapsing multiple sclerosis
✍ Scribed by Dr Jack H. Simon; Lawrence D. Jacobs; Marilyn Campion; Karl Wende; Nancy Simonian; Diane L. Cookfair; Richard A. Rudick; Robert M. Herndon; John R. Richert; Andres M. Salazar; John J. Alam; Jill S. Fischer; Donald E. Goodkin; Carl V. Granger; Michelle Lajaunie; Anna L. Martens-Davidson; Maryjoel Meyer; Jeanelle Sheeder; Kim Choi; Ann L. Scherzinger; David M. Bartoszak; Dennis N. Bourdette; Jonathan Braiman; Carol M. Brownscheidle; Michael E. Coats; Stanley L. Cohan; David S. Dougherty; Revere P. Kinkel; Michele K. Mass; Fredrick E. Munschauer III; Roger L. Priore Scd; Patrick M. Pullicino; Barbara J. Scherokman; Bianca Weinstock-Guttman; Ruth H. Whitham
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 862 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
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The PRISMS (Prevention of Relapses and Disability by Interferon-1a Subcutaneously in Multiple Sclerosis) trial was a doubleblind, randomized, multicenter, phase III, placebo-controlled study of interferon-1a in 560 patients from 22 centers in 9 countries with clinically definite or laboratory-supp
We extend sincere congratulations to Dr Jacobs and colleagues for the successful conclusion of their study of recombinant interferon p l a (rIFN-pla) in patients with multiple sclerosis (MS). The impressive results showed that 6 million international units of rIFN-Pla applied once weekly via the int
## Abstract ## Objective Recent findings support greater efficacy of early vs. delayed interferon beta (IFNβ) treatment in patients with a first clinical event suggestive of multiple sclerosis (MS). We aimed to evaluate the effectiveness of early IFNβ treatment in definite relapsing‐remitting MS (