✦ LIBER ✦

Cerebral sarcoidosis presenting as supranuclear gaze palsy with hypokinetic rigid syndrome

✍ Scribed by Dr. U. Schlegel; P. Clarenbach; Almut Cordt; A. Steudel

Book ID: 102506990
Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 361 KB
Volume: 4
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.870040309

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✦ Synopsis

A 31-year-old man with histologically documented pulmonary sarcoidosis developed a severe hypokinetic rigid syndrome with a supranuclear gaze palsy following recurrent lymphocytic meningitis and occlusive hydrocephalus. Magnetic resonance imaging (MRI) showed multiple hyperintense foci in the CNS, not detectable by computed tomography (CT). Long-term steroid therapy led to clinical complete remission.

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## Abstract We describe a 68‐year‐old woman who presented with falls, mild limb bradykinesia, axial rigidity, and a severe supranuclear gaze palsy, which failed to benefit from levodopa. She subsequently developed severe apraxia, progressive dysarthria, dysphagia, and a frontal cognitive impairment