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Cerebral ischemia-induced apoptosis and necrosis in normal and diabetic rats: Effects of insulin and C-peptide

✍ Scribed by Natalie N. Rizk; José A. Rafols; Joseph C. Dunbar


Book ID
113501736
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
602 KB
Volume
1096
Category
Article
ISSN
0006-8993

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The effects of synthetic rat C-peptide 1 and C-peptide 2 on plasma insulin and blood glucose concentrations in the rat were studied. Infusion of rat C-peptide (500 micrograms X h-1 X kg-1) diminished glucose induced increase of plasma insulin by 56% (15.2 +/- 0.9 versus 6.6 +/- 0.6 ng/ml, p less tha