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Cerebral Intracellular Changes During Supercarbia: An In Vivo31P Nuclear Magnetic Resonance Study in Rats

✍ Scribed by Litt, Lawrence; Gonzalez-Mendez, Ricardo; Severinghaus, John W.; Hamilton, William K.; Shuleshko, Julia; Murphy-Boesch, Joseph; James, Thomas L.


Book ID
109869664
Publisher
Nature Publishing Group
Year
1985
Tongue
English
Weight
556 KB
Volume
5
Category
Article
ISSN
0271-678X

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An in vivo31P NMR study of cerebral hypo
✍ Lawrence Litt; Ricardo GonzΓ‘lez-MΓ©ndez; Philip R. Weinstein; John W. Severinghau πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 457 KB πŸ‘ 1 views

Twenty minutes of hypoxic hypoxia in five anesthetized rats reversibly reduced cerebral PCr and pH while ATP stayed constant. Complete metabolic and neurologic recovery occurred after oxygen was restored. Careful control of physiological parameters resulted in metabolite changes that were the same,