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Ceramides and acylceramides in human epidermis

✍ Scribed by Hamanaka, Sumiko; Nakazawa, Shuichi; Suzuki, Minoru; Suzuki, Akemi; Otsuka, Fujio


Book ID
122553275
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
152 KB
Volume
16
Category
Article
ISSN
0923-1811

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The sphingolipids la, b and 2a, b, which play important roles in epidermal barrier function, were synthesized by N-acylation of C,,-sphingosine 3 and I-0-glucosylated C,,-sphingosine 6, respectively, with w-acyloxy-substituted fatty acids 4 and 5 (Scheme 1 ) . These fatty acids were obtained from w-