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Ceramide induces apoptosis in human lung adenocarcinoma A549 cells through mitogen-activated protein kinases

✍ Scribed by Tian-hua ZHANG; Jian-feng LIU; Yao ZHANG; Yong-li LI; Hai-tao LU; Nobuo MURATA; Tatsuo YAMAKAWA

Book ID: 111355152
Publisher: Nature Publishing Group
Year: 2007
Tongue: Chinese
Weight: 781 KB
Volume: 28
Category: Article
ISSN: 1671-4083
DOI: 10.1111/j.1745-7254.2007.00505.x

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## Abstract Human __PNAS4__ (h__PNAS4__) is a recently identified pro‐apoptosis gene, which is able to induce apoptosis in A549 human lung adenocarcinoma cells following its overexpression. In this work, we investigated the changes of protein profile in h__PNAS4__‐induced apoptosis in A549 cells th