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Ceramide-1-phosphate: a novel regulator of cell activation

✍ Scribed by Antonio Gómez-Muñoz


Book ID
117106357
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
119 KB
Volume
562
Category
Article
ISSN
0014-5793

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A novel regioselective synthesis of D-erythro -sphingosine 1-phosphate and D-erythro -ceramide 1-phosphate is described. The synthesis is based upon (1) in situ oxidative phosphorylation of the primary hydroxyl group in N-Boc-D-erythro-sphingosine utilizing trimethyl phosphite and carbon tetrabromid