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Central nervous system metastases in breast cancer patients administered trastuzumab

✍ Scribed by Renata Duchnowska; Cezary Szczylik


Book ID
116394967
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
123 KB
Volume
31
Category
Article
ISSN
0305-7372

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## Abstract ## BACKGROUND Trastuzumab, which is a large monoclonal antibody that is efficacious in the treatment of patients with HER‐2/__neu__‐overexpressing, metastatic breast carcinoma, does not penetrate the blood‐brain barrier and, thus, may allow the brain to become a sanctuary site for micr