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Cellular uptake of covalent conjugates of oligonucleotide with membrane-modifying peptide, peptaibol

✍ Scribed by Shun-ichi Wada; Yasunari Hitora; Saori Yokoe; Osamu Nakagawa; Hidehito Urata


Book ID
113495792
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
425 KB
Volume
20
Category
Article
ISSN
0968-0896

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✍ Yvonne Turner; Gerd Wallukat; Pille SÀÀlik; Burkhard Wiesner; Stephan Pritz; Joh πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 383 KB

## Abstract A 12‐mer peptide nucleic acid (PNA) directed against the nociceptin/orphanin FQ receptor mRNA was disulfide bridged with various peptides without and with cell‐penetrating features. The cellular uptake and the antisense activity of these conjugates were assessed in parallel. Quantitatio