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Cellular uptake of cationic gadolinium-DOTA peptide conjugates with and without N-terminal myristoylation

✍ Scribed by A. Sturzu; U. Klose; H. Echner; A. Beck; A. Gharabaghi; H. Kalbacher; S. Heckl


Publisher
Springer
Year
2008
Tongue
English
Weight
370 KB
Volume
37
Category
Article
ISSN
0939-4451

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## Abstract A 12‐mer peptide nucleic acid (PNA) directed against the nociceptin/orphanin FQ receptor mRNA was disulfide bridged with various peptides without and with cell‐penetrating features. The cellular uptake and the antisense activity of these conjugates were assessed in parallel. Quantitatio