Cellular transformation by SV40 large T antigen: interaction with host proteins
β Scribed by Syed Hamid Ali; James A. DeCaprio
- Book ID
- 112265013
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 183 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1044-579X
No coin nor oath required. For personal study only.
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## Abstract Simian virus 40 large T antigen, human papilloma virus E7 and adenovirus E1A are all potent oncoproteins that can induce several types of tumours. One of the major functions of these oncoproteins is to interact with the retinoblastoma tumour suppressor protein, Rb, a master switch of th