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Insulin-induced mitogenesis associated with transformation by the SV40 large T antigen

✍ Scribed by Hanlin Wang; Robert E. Scott

Book ID: 102885852
Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 971 KB
Volume: 147
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1041470114

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✦ Synopsis

Simian virus 40 (SV40) large T antigen-transformed cells typically show a markedly reduced serum requirement for growth and the inability to growth arrest and differentiate. An SV40 large T antigen-transformed 3T3 T cell line, CSV3-1, that can growth arrest and differentiate into adipocytes with high efficiency has, however, recently been described (Scott et al: Proc.

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