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Cellular pharmacology and biological activity of 5-carboranyl-2′-deoxyuridine

✍ Scribed by Raymond F. Schinazi; Naganna M. Goudgaon; Geraldine Fulcrand; Yahya El Kattan; Zbigniew Lesnikowski; Giliyar Ullas; Joseph Moravek; Dennis C. Liotta

Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
932 KB
Volume
28
Category
Article
ISSN
0360-3016

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Synthesis and Biological Activity of Bis(pivaloyloxymethyl) Ester of 2'-Azido-2'-deoxyuridine 5'-Monophosphate. -The title compound (III) which is the membrane-permeable prodrug of the phosphate (I), is evaluated with positive results for inhibition of cell growth with 60 tumor cell lines.