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ChemInform Abstract: Biological Activity and Phosphorylation of 2′-Azido-2′-deoxyuridine and 2′-Azido-2′-deoxycytidine.

✍ Scribed by S. H. KANG; M. J. CHO

Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis and Biolo
ChemInform Abstract: Synthesis and Biological Activity of Bis(pivaloyloxymethyl) Ester of 2′-Azido-2′-deoxyuridine 5′-Monophosphate.
✍ S. H. KANG; A. K. SINHABABU; M. J. CHO 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 1 views

Synthesis and Biological Activity of Bis(pivaloyloxymethyl) Ester of 2'-Azido-2'-deoxyuridine 5'-Monophosphate. -The title compound (III) which is the membrane-permeable prodrug of the phosphate (I), is evaluated with positive results for inhibition of cell growth with 60 tumor cell lines.