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Cellular peptide composition governed by major histocompatibility complex class I molecules

✍ Scribed by Falk, Kirsten; Rötzschke, Olaf; Rammensee, Hans-Georg


Book ID
109766487
Publisher
Nature Publishing Group
Year
1990
Tongue
English
Weight
431 KB
Volume
348
Category
Article
ISSN
0028-0836

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Major histocompatibility complex class I (MHC-I) molecules sample peptides from the intracellular environment and present them to cytotoxic T cells (CTL). To establish a selection system, and, thereby, enable a library approach to identify the specificities involved (that of the MHC-I for peptides a