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Cellular Electron Transfer and Radical Mechanisms for Drug Metabolism

✍ Scribed by John E. Biaglow

Book ID
124667027
Publisher
Bioone
Year
1981
Tongue
English
Weight
852 KB
Volume
86
Category
Article
ISSN
0033-7587

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A new family of photonuclease, thiadiazole-naphthalimide were synthesized and evaluated. Thiadiazole group was incorporated for the first time. These compounds intercalated into DNA efficiently and damaged DNA as low as 10 mM photochemically. Mechanism experiment showed that electron transfer and ra