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Cellular characterization of cells from the Fanconi anemia complementation group, FA-D1/BRCA2

✍ Scribed by Barbara C. Godthelp; Paul P.W. van Buul; Nicolaas G.J. Jaspers; Elhaam Elghalbzouri-Maghrani; Annemarie van Duijn-Goedhart; Fré Arwert; Hans Joenje; Małgorzata Z. Zdzienicka


Book ID
113808908
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
593 KB
Volume
601
Category
Article
ISSN
0027-5107

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Fanconi anemia (FA) is a rare autosomal recessive or X-linked disorder characterized by aplastic anemia, cancer susceptibility and cellular sensitivity to DNA crosslinking agents. Eight FA proteins (FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL and FANCM) and three non-FA proteins (FAAP100, FAAP24