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Complementation Analysis in Fanconi Anemia: Assignment of the Reference FA-H Patient to Group A

✍ Scribed by Hans Joenje; Marieke Levitus; Quinten Waisfisz; Alan D'Andrea; Irene Garcia-Higuera; Tommy Pearson; Carola G.M. van Berkel; Martin A. Rooimans; Neil Morgan; Christopher G. Mathew; Fré Arwert


Book ID
117853419
Publisher
American Society of Human Genetics
Year
2000
Tongue
English
Weight
348 KB
Volume
67
Category
Article
ISSN
0002-9297

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Fanconi anemia (FA) is a rare autosomal recessive or X-linked disorder characterized by aplastic anemia, cancer susceptibility and cellular sensitivity to DNA crosslinking agents. Eight FA proteins (FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL and FANCM) and three non-FA proteins (FAAP100, FAAP24