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Cellular APOBEC3G restricts HIV-1 infection in resting CD4+ T cells

✍ Scribed by Chiu, Ya-Lin; Soros, Vanessa B.; Kreisberg, Jason F.; Stopak, Kim; Yonemoto, Wes; Greene, Warner C.

Book ID
109899064
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
41 KB
Volume
466
Category
Article
ISSN
0028-0836

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## Abstract Allogeneic immunity is one of the most potent natural immune responses. APOBEC3G (A3G) is an intracellular anti‐viral factor that deaminates cytidine to uridine. Allogeneic stimulation of human CD4^+^ T cells __in vitro__ upregulated A3G mRNA and a significant correlation was found betw