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Cellular Activation of the Self-Quenched Fluorescent Reporter Probe in Tumor Microenvironment

โœ Scribed by Bogdanov, Alexei A.; Lin, Charles P.; Simonova, Maria; Matuszewski, Lars; Weissleder, Ralph


Book ID
122318693
Publisher
Neoplasia Press
Year
2002
Tongue
English
Weight
193 KB
Volume
4
Category
Article
ISSN
1522-8002

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The ratio of peak III to peak I intensities of the so-called III and I fluorescence bands of pyrene increases dramatically when cupric ions are used as quenchers for pyrene emission in sodium dodecyl sulfate micelles. These results indicate a decrease in the polarity sensed by the probe when its lif