Cell-type specificity of anti-CD45 autoantibodies in systemic lupus erythematosus
β Scribed by Jan Czyzyk; Philip Fernsten; Melody Shaw; John B. Winfield
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 878 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Antibody a c t i v i t y t o various histones was examined i n a s o l i d phase radioimmunoassay. More than one h a l f o f the sera from systemic lupus erythematosus (SLE) p a t i e n t s had IgM a c t i v i t y t o t o t a l histones, and a s l i g h t l y lower frequency was observed f o r IgG a
## Abstract Twentyβone sera from 11 patients with systemic lupus erythematosus were titrated with ^125^Iβssβcalf thymus DNA to determine their maximum capacity to bind DNA. Only five sera were capable of binding > 90% of the input DNA. The remaining sixteen sera showed maximum DNA binding levels be