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Cell-type Specific Changes in Cytokine-STAT Signal Transduction Stage Systemic Lupus Erythematosus

✍ Scribed by Matthew Hale; Peter Krutzik; Garry Nolan

Book ID
113539554
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
58 KB
Volume
123
Category
Article
ISSN
1090-2341

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## Abstract ## Objective Beta 1 integrin is a representative adhesion molecule for cell–cell and cell–extracellular matrix interactions, and it provides costimulatory signals to T cells. However, the relevance of Ξ²1 integrin to T cell activation in systemic lupus erythematosus (SLE) remains unclea