Cell transfection with polycationic cyclodextrin vectors
✍ Scribed by Sally-Ann Cryan; Ann Holohan; Ruth Donohue; Raphael Darcy; Caitriona M O’Driscoll
- Book ID
- 113591302
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 297 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0928-0987
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Background The delivery of genes to the airways holds promise for the treatment of lung diseases such as cystic ®brosis and asthma. Current nonviral gene delivery systems lack suf®cient transfection ef®ciency. Pulmonary surfactant has been reported to be a barrier to gene transfer into the airways.
## Abstract ## Background Syngeneic vascular cells are interesting tools for indirect gene therapy in the cardiovascular system. This study aims to optimize transfection conditions of primary cultures of vascular smooth muscle cells (VSMCs) using different non‐viral vectors and zinc as an adjuvant