Cell Therapy: Current Status and Future Directions

✍ Scribed by Dwaine F. Emerich, Gorka Orive (eds.)

• Publisher: Humana Press
• Year: 2017
• Tongue: English
• Leaves: 334
• Series: Molecular and Translational Medicine
• Edition: 1
• Category: Library

✦ Synopsis

This volume provides a comprehensive, state-of-the art review of the field of cell therapy. The volume begins with an overview of the breadth of the field and then turns to overviews of imaging technologies that can aid in both safety and efficacy evaluations. The book then turns to numerous contributions detailing the rapidly growing field of stem cell therapies. These sections cover our understanding of the natural roles of stem cells in biology and human disease and then touches on several of the more prominent areas where stem cells are moving rapidly into clinical evaluation including neurodegenerative diseases, muscular dystrophy, cardiac repair, and diabetes. The volume concludes with contributions from experts in oncology, ophthalmology, stem cells, 3-D printing, and biomaterials where the convergence of expertise is leading to unprecedented insights into how to minutely control the in vivo fate and function of transplanted and/or endogeneously mobilized cells. Finally, the book provides insights into the pivotal relationship between academic and industrial partnerships.

This volume is designed to touch on the major areas where the field will make its greatest and most immediate clinical impacts. This text will provide a useful resource for physicians and researchers interested in the rapidly changing filed of cell therapy.

✦ Table of Contents

Front Matter ....Pages i-xv
Molecular Considerations in Cell Transplant Imaging (Aline M. Thomas, Jeff W. M. Bulte)....Pages 1-17
Considerations for Successful Encapsulated β-Cell Therapy (Christopher G. Thanos, Jason L. Gaglia, Felicia W. Pagliuca)....Pages 19-52
Stem Cell Therapy for Neurovascular and Traumatic Brain Diseases (Marci G. Crowley, M. Grant Liska, Cesar V. Borlongan)....Pages 53-72
Cell Replacement Strategies for Parkinson’s Disease (Diptaman Chatterjee, Dustin R. Wakeman, Jeffrey H. Kordower)....Pages 73-83
Cell Therapy for Epilepsy (Chiara Falcicchia, Giovanna Paolone, Michele Simonato)....Pages 85-97
Dendritic Cell-Based Cancer Therapies: Current Status and Future Directions (Shah Md. Shahjahan Miah, Timothy K. Erick, Dwaine F. Emerich)....Pages 99-120
Encapsulation Approaches to Cell Therapy (Paul de Vos)....Pages 121-138
Biomaterials and Cells for Revascularization (Priscilla A. Williams, Kevin T. Campbell, Eduardo A. Silva)....Pages 139-172
Cell Reprogramming for Cardiac Regeneration and Rare Disease Modeling (Xonia Carvajal-Vergara, Juan Roberto Rodríguez-Madoz, Beatriz Pelacho, Felipe Prósper)....Pages 173-196
Engineering Organoid Systems to Model Health and Disease (James A. Ankrum, Thomas J. Bartosh, Xiaolei Yin, Alexander J. Brown, Anthony J. Burand Jr, Lauren Boland)....Pages 197-226
3D Printing for Cell Therapy Applications (Ashley N. Leberfinger, Kazim Kerim Moncal, Dino J. Ravnic, Ibrahim T. Ozbolat)....Pages 227-248
Cell Therapy for Ophthalmic Diseases (Konrad Kauper, Arne Nystuen)....Pages 249-279
Cell Therapy: Approaching a Partnership with Pharma (Vincent Ling)....Pages 281-295
Stem Cell Therapy in Duchenne Muscular Dystrophy (Mirella Meregalli, Marzia Belicchi, Yvan Torrente)....Pages 297-317
Back Matter ....Pages 319-326

✦ Subjects

Pathology