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Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands

✍ Scribed by Thomas J. Ketas; Shawn E. Kuhmann; Ashley Palmer; Juan Zurita; Weijing He; Sunil K. Ahuja; Per Johan Klasse; John P. Moore


Book ID
113947196
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
469 KB
Volume
364
Category
Article
ISSN
0042-6822

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## Abstract Within the brain, HIV‐1 targets the microglia and astrocytes. Previous studies have reported that viral entry into astrocytes is independent of CD4, in contrast to microglia. We aimed to determine whether chemokine receptors play a role in mediating CD4‐independent HIV‐1 entry into astr