𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cell surface display of a lysosomal enzyme for extracellular gene-directed enzyme prodrug therapy

✍ Scribed by Heine, D; Müller, R; Brüsselbach, S

Book ID
110038938
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
940 KB
Volume
8
Category
Article
ISSN
0969-7128

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

A daunorubicin β-galactoside prodrug for
A daunorubicin β-galactoside prodrug for use in conjunction with gene directed enzyme prodrug therapy
✍ Ajit K Ghosh; Saeed Khan; Frank Marini; J.Arly Nelson; David Farquhar 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 124 KB

N-[4-(b-d-Galactopyranosyl)-3-nitrobenzyloxycarbonyl]daunomycin was synthesized as a neutral prodrug of daunomycin. Although stable in 0.05 M phosphate buer, pH 7.4 at 37 C, it was rapidly converted to daunomycin and 3-nitro-4-hydroxybenzyl alcohol under the same conditions in the presence of E. col