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Cell Proliferation Rates in Common Cancer Target Tissues of B6C3F1 Mice and F344 Rats: Effects of Age, Gender, and Choice of Marker

โœ Scribed by Sandra R. Eldridge; Susan M. Goldsworthy

Book ID
115608663
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
237 KB
Volume
32
Category
Article
ISSN
0272-0590

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Glycidol, a simple aliphatic epoxide, was administered by gavage in water to groups of male and female F344/N rats and B6C3F1 mice. Rats received 0, 37.5 or 75 mg kg-' and mice received 0, 25 or 50 mg kg-' daily, 5 days per week for 2 years. Exposure to glycidol was associated with dose-related incr