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Cell polarity pathways converge and extend to regulate neural tube closure

โœ Scribed by Irene E. Zohn; Catherine R. Chesnutt; Lee Niswander

Book ID
114322961
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
90 KB
Volume
13
Category
Article
ISSN
0962-8924

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## Abstract Closure of the neural tube is essential for normal development of the brain and spinal cord. Failure of closure results in neural tube defects (NTDs), common and clinically severe congenital malformations whose molecular mechanisms remain poorly understood. On the other hand, it is incr