## Abstract Closure of the neural tube is essential for normal development of the brain and spinal cord. Failure of closure results in neural tube defects (NTDs), common and clinically severe congenital malformations whose molecular mechanisms remain poorly understood. On the other hand, it is incr
โฆ LIBER โฆ
Epithelial cell polarity genes are required for neural tube closure
โ Scribed by Kit Doudney; Philip Stanier
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 166 KB
- Volume
- 135C
- Category
- Article
- ISSN
- 1552-4868
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## Abstract ## BACKGROUND Neural tube closure is a critical embryological process that requires the coordination of many molecular and cellular events. Only recently has the molecular basis of the cell movements that drive neural tube closure begun to be elucidated. This has been accomplished in p