Cell Polarity 2: Role in Development and Disease

✍ Scribed by Klaus Ebnet (eds.)

Publisher: Springer International Publishing
Year: 2015
Tongue: English
Leaves: 228
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

This work provides a state-of-the art overview on the most relevant aspects of cell polarity.

Volume 2 discusses the physiological and pathophysiological relevance of cell polarity. It especially focuses on pathophysiological conditions in which one or several aspects of cell polarity are impaired, and in which a loss of cell polarity possibly contributes to disease (e.g. epithelial-to-mesenchymal transition in cancer, role of polarity proteins in cancer).

Both volumes are intended for professors, group leaders and researchers in cell biology as well as for medical professionals working in anatomy, cell biology, physiology, pathology and tumor biology.

✦ Table of Contents

Front Matter....Pages i-viii
Front Matter....Pages 1-1
Cell Polarity in One-Cell C. elegans Embryos: Ensuring an Accurate and Precise Spatial Axis During Development....Pages 3-32
Establishment and Maintenance of Cell Polarity in the C. elegans Intestine....Pages 33-65
Apicobasal Polarity and Lumen Formation During Development....Pages 67-92
Front Matter....Pages 93-93
Asymmetric Cell Division and Development of the Central Nervous System in Drosophila ....Pages 95-117
Polarity Control of Spindle Positioning in the C. elegans Embryo....Pages 119-141
Front Matter....Pages 143-143
Par Proteins in Tumor Formation and Progression....Pages 145-165
Cell Polarity: A Key Defence Mechanism Against Infection and Cancer Cell Invasion?....Pages 167-186
Cell Polarity in Mammary Gland Morphogenesis and Breast Cancer....Pages 187-207
Front Matter....Pages 209-209
Cellular Polarity and Pathogenicity....Pages 211-226
Back Matter....Pages 227-228

✦ Subjects

Cell Biology; Developmental Biology; Cancer Research; Human Physiology

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