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Stem Cells in Development and Disease

✍ Scribed by Michael Rendl (Eds.)


Publisher
Academic Press
Year
2014
Tongue
English
Leaves
453
Series
Current Topics in Developmental Biology 107
Edition
1
Category
Library

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✦ Synopsis


This new volume of Current Topics in Developmental Biology covers Stem Cells in Development and Disease. The chapters provide a comprehensive set of reviews covering such topics as the mechanisms of pluripotency in vivo and in vitro, hematopoietic stem cell development, intestinal stem cells and their defining niche, epithelial stem cells in adult skin, the mammary stem cell hierarchy, satellite cells, neural stem cells of the hippocampus, lung stem and progenitor cells in tissue homeostasis and disease, spermatogonial stem cell functions in physiological and pathological conditions, the origin, biology, and therapeutic potential of facultative adult hepatic progenitor cells, nephron progenitor cells, adult stem cell niches, cancer stem cells, pluripotency and cellular heterogeneity, and cellular mechanisms of somatic stem cell aging

  • Covers the area of Stem Cells in Development and Disease
  • International board of authors
  • Provides a comprehensive set of reviews covering such topics as Intestinal Stem Cells, Nephron Stem Cells/Progenitors, Skin epithelial Stem Cells and Lung Stem Cells

✦ Table of Contents


Content:
Series Page
Page ii

Copyright
Page iv

Contributors
Pages xi-xiii

Preface
Pages xv-xviii
Michael Rendl

Chapter One - Mechanisms of Pluripotency In Vivo and In Vitro
Pages 1-37
Eszter Posfai, Oliver H. Tam, Janet Rossant

Chapter Two - Hematopoietic Stem Cell Development: An Epigenetic Journey
Pages 39-75
Sean M. Cullen, Allison Mayle, Lara Rossi, Margaret A. Goodell

Chapter Three - Intestinal Stem Cells and Their Defining Niche
Pages 77-107
David Wei-Min Tan, Nick Barker

Chapter Four - Epithelial Stem Cells in Adult Skin
Pages 109-131
Ana Mafalda Baptista Tadeu, Valerie Horsley

Chapter Five - The Mammary Stem Cell Hierarchy
Pages 133-160
Naiyang Fu, Geoffrey J. Lindeman, Jane E. Visvader

Chapter Six - Satellite Cells: The Architects of Skeletal Muscle
Pages 161-181
Natasha C. Chang, Michael A. Rudnicki

Chapter Seven - Neural Stem Cell of the Hippocampus: Development, Physiology Regulation, and Dysfunction in Disease
Pages 183-206
Chiara Rolando, Verdon Taylor

Chapter Eight - Lung Stem and Progenitor Cells in Tissue Homeostasis and Disease
Pages 207-233
Kristen T. Leeman, Christine M. Fillmore, Carla F. Kim

Chapter Nine - Spermatogonial Stem Cell Functions in Physiological and Pathological Conditions
Pages 235-267
Qi-En Yang, Jon M. Oatley

Chapter Ten - The Origin, Biology, and Therapeutic Potential of Facultative Adult Hepatic Progenitor Cells
Pages 269-292
Soona Shin, Klaus H. Kaestner

Chapter Eleven - Nephron Progenitor Cells: Shifting the Balance of Self-Renewal and Differentiation
Pages 293-331
Raphael Kopan, Shuang Chen, Melissa Little

Chapter Twelve - Adult Stem Cell Niches: Cellular and Molecular Components
Pages 333-372
AmΓ©lie Rezza, Rachel Sennett, Michael Rendl

Chapter Thirteen - Cancer Stem Cells, Pluripotency, and Cellular Heterogeneity: A WNTer Perspective
Pages 373-404
Yaser Atlasi, Leendert Looijenga, Riccardo Fodde

Chapter Fourteen - Cellular Mechanisms of Somatic Stem Cell Aging
Pages 405-438
Yunjoon Jung, Andrew S. Brack

Index
Pages 439-452


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