Cell-penetrating peptides: small from inception to application
✍ Scribed by Magzoub, Mazin; Gräslund, Astrid
- Book ID
- 111860645
- Publisher
- Cambridge University Press
- Year
- 2004
- Tongue
- English
- Weight
- 458 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0033-5835
No coin nor oath required. For personal study only.
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Recent years have seen a surge in interest in cell-penetrating peptides (CPP) as an efficient means for delivering therapeutic targets into cellular compartments. The cell membrane is impermeable to hydrophilic substances yet linking to CPP can facilitate delivery into cells. Thus the unique translo
## Abstract Cell membranes act as protective walls to exclude most molecules that are not actively imported by living cells. This is an efficient way for a cell to prevent uncontrolled influx or efflux of solutes, which otherwise would be harmful to it. Only compounds within a narrow range of molec