Cell kinetics of medulloblastomas
β Scribed by Satoyuki Lto; Takao Hoshino; Michael D. Prados; Michael S. B. Edwards
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 757 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0008-543X
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## Abstract ## BACKGROUND. Histopathologic evaluation of the degree and extent of anaplasia is a useful prognostic parameter in pediatric medulloblastomas. Whether the same applies to adult medulloblastomas is not known. ## METHODS. The study included 74 adult patients with histologically confir
## Abstract Our group has previously demonstrated a high frequency of allelic loss on the short arm of chromosome 8 and identified a region of homozygous deletion of 1.41 Mb, flanked by D8S520 and D8S1130, on 8p23.1 in medulloblastomas, suggesting the presence of a tumor suppressor gene in this cri
## Abstract The classic medulloblastoma (CMB) and the desmoplastic medulloblastoma (DMB) subtypes represent the major medulloblastoma variants. In contrast to CMB, DMB display high levels of the lowβaffinity nerve growth factor receptor p75^NTR^. Given the reports of a better clinical course of DMB