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Cell growth, cell division and cell size homeostasis in Swiss 3T3 cells

✍ Scribed by Robert F. Brooks; Robert Shields


Book ID
115891958
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
393 KB
Volume
156
Category
Article
ISSN
0014-4827

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Proliferating nonconfluent 3T3 cells become committed to proceed through the cell cycle or to enter Go during the first post-mitotic part of GI (G,pm). The decision to proceed through G,pm is dependent on the presence of serum growth factors in the culture medium. Cells that have passed this particu

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## Abstract In sub‐confluent cultures of Balb/c‐3T3 cells, pinocytosis rates were increased after exposure to specific growth factors (serum; platelet‐derived growth factor, PDGF; epidermal growth factor, EGF). Conversely, as cells became growth‐inhibited with increasing culture density, there was