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Cell cycle G2/M arrest and activation of cyclin-dependent kinases associated with low-dose paclitaxel-induced sub-G1 apoptosis

✍ Scribed by C.-H. Shu; W. K. Yang; Y.-L. Shih; M.-L. Kuo; T.-S. Huang

Book ID: 111561794
Publisher: Springer
Year: 1997
Tongue: English
Weight: 924 KB
Volume: 2
Category: Article
ISSN: 1360-8185
DOI: 10.1023/a:1026422111457

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## Abstract In this study, we first demonstrated that loratadine (LOR), a promising world widely used oral anti‐histamine, effectively inhibits growth of tumors derived from human colon cancer cells (COLO 205) in an in vivo setting. In vitro study demonstrated that the anti‐tumor effects of LOR in