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Cell-based ciliary neurotrophic factor therapy against Alzheimer's disease

✍ Scribed by Garcia, Pierre; Youssef, Ihsen; Utvik, Jo; Florent-Béchard, Sabrina; Kriem, Badreddine; Oster, Thierry; Niclou, Simone; Pillot, Thierry


Book ID
122651657
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
50 KB
Volume
5
Category
Article
ISSN
1552-5260

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Ciliary neurotrophic factor (CNTF) is a cytokine that has been reported to affect cellular differentiation. Mouse CNTF knockouts have progressive motor neuron atrophy, but this protein has uncertain physiological function in humans. A naturally occurring CNTF variant in man, observed in many populat