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Glial Cell Derived Neurotrophic Factors and Alzheimer's Disease

✍ Scribed by Ambrish J. Patel; Colin Wickenden; Angela Jen; H.A.Rohan de Silva


Book ID
118769278
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
310 KB
Volume
5
Category
Article
ISSN
1055-8330

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Glial cell line-derived neurotrophic factor (GDNF) was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson's disease. GDNF is a more potent survival factor for dopaminergic neurons and the noradrenerg