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Cell apoptosis induced by zinc deficiency in osteoblastic MC3T3-E1 cells via a mitochondrial-mediated pathway

✍ Scribed by Baolei Guo; Maowei Yang; Dan Liang; Lei Yang; Junjun Cao; Le Zhang


Publisher
Springer
Year
2011
Tongue
English
Weight
532 KB
Volume
361
Category
Article
ISSN
0300-8177

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In this study, we have found that Escherichia coli lipopolysaccharide (LPS) could induce the expression of pentraxin 3 (PTX3) mRNA in osteoblast-like cells (MC 3T3-E1) dose dependently. The relation between this expression and alkaline phosphatase (ALP), mitogen-activated protein kinases (MAPKs), an