Celiprolol: Its profile as a potential antiarrhythmic agent
โ Scribed by Thaddeus P. Pruss
- Book ID
- 115658368
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 342 KB
- Volume
- 116
- Category
- Article
- ISSN
- 1097-6744
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๐ SIMILAR VOLUMES
N-Ethylation of substituted ethyl 1H-indole-2-carboxylates with iodoethane and potassium carbonate gave substituted ethyl 1-ethyl-1H-indole-2-carboxylates. The later compounds on treatment with a range of aryl amines with varying structural complexity, gave the desired ethyl 1H-indole-2-carboxamide
Iodinated and radioiodinated analogs of propranolol and N,N-dimethylpropranolol were synthesized wherein an iodophenyl moiety replaced the naphthalene ring of the parent drug. These new compounds were evaluated not only for their beta-adrenergic blocking and antiarrhythmic activities but also for th