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CDKN1C/p57kip2is a candidate tumor suppressor gene in human breast cancer

✍ Scribed by Pamela S Larson; Benjamin L Schlechter; Chia-Lin King; Qiong Yang; Chelsea N Glass; Charline Mack; Robert Pistey; Antonio de las Morenas; Carol L Rosenberg

Book ID: 115011485
Publisher: BioMed Central
Year: 2008
Tongue: English
Weight: 442 KB
Volume: 8
Category: Article
ISSN: 1471-2407
DOI: 10.1186/1471-2407-8-68

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## Abstract Extensive hypermethylation and consecutive transcriptional silencing of tumorsuppressor genes have been documented in multiple tumor entities including breast cancer. In a microarray based genome‐wide methylation analysis of five sporadic breast carcinomas we identified a hypermethylate