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Cdk2 acts upstream of mitochondrial permeability transition during paclitaxel-induced apoptosis

✍ Scribed by Xiao-Xi Guo; Hanna Kim; Yang Li; Hyungshin Yim; Seung Ki Lee; Ying-Hua Jin


Book ID
107692125
Publisher
SP Higher Education Press
Year
2011
Tongue
English
Weight
611 KB
Volume
2
Category
Article
ISSN
1674-800X

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Acetaminophen overdose causes massive hepatic failure via mechanisms involving glutathione depletion, oxidative stress, and mitochondrial dysfunction. The ultimate target of acetaminophen causing cell death remains uncertain, and the role of apoptosis in acetaminophen-induced cell killing is still c