CD95 ligand is expressed in Reed–Sternberg cells of Hodgkin’s disease
✍ Scribed by Isao Sakuma; Tadashi Yoshino; Kunihiro Omonishi; Ritsuo Nishiuchi; Norihiro Teramoto; Hiroyuki Yanai; Kunimitsu Kawahara; Ichiro Kubonishi; Yoshinobu Matsuo; Tadaatsu Akagi
- Book ID
- 114430801
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 292 KB
- Volume
- 49
- Category
- Article
- ISSN
- 1320-5463
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## Abstract There has been substantial advances in our understanding of the nature of the Hodgkin/Reed–Sternberg (H/RS) cell in recent years. There is now compelling evidence that the H/RS cells in the vast majority of cases of classical Hodgkin's disease (CHD) are derived from the B‐cell lineage a
## Abstract EBV DNA has been detected by Southern blot hybridization in 20‐25% of Hodgkin's disease tumor specimens and localized to the Reed‐Sternberg cells by __in situ__ hybridization. In the present investigation we used a ^3^H‐labelled EBER I anti‐sense RNA for __in situ__ hybridization of arc