CD8αα homodimer expression and role in CD8 T cell memory generation during influenza virus A infection in mice
✍ Scribed by Weimin Zhong; Ellis L. Reinherz
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 360 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0014-2980
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## Abstract Activation of mature CD8^+^ T cells requires recognition, __via__ the T cell receptor (TCR), of peptide + MHC (pMHC) complexes with an avidity that exceeds a designated threshold. Multiple indicators of T cell avidity have been described that provide unique information on the characteri