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CD8+ T cell tolerance following antigen recognition on hepatocytes

✍ Scribed by Lauren E. Holz; Alessandra Warren; David G. Le Couteur; David G. Bowen; Patrick Bertolino

Book ID
118470567
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
975 KB
Volume
34
Category
Article
ISSN
0896-8411

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## Abstract The 5T4 oncofetal antigen is expressed by a wide variety of human carcinomas, including colorectal, ovarian and gastric carcinomas. The restricted expression of 5T4 on tumor tissues as well as its implication in tumor progression and bad prognosis makes 5T4 a promising new candidate for