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CD8 blockade promotes the expansion of antigen-specific CD4+ FOXP3+ regulatory T cells in vivo

✍ Scribed by Z. Wang; J.D. Davies

Book ID
116576102
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
942 KB
Volume
7
Category
Article
ISSN
1567-5769

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## Abstract Interleukin‐2 (IL‐2) treatment is currently used to enhance T cell‐mediated immune responses against tumors or in viral infections. At the same time, IL‐2 is essential for the peripheral homeostasis of CD4^+^CD25^+^Foxp3^+^ regulatory T cells (Treg). In our study, we show that IL‐2 is a