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CD74 Is a Novel Prognostic Factor for Patients with Pancreatic Cancer Receiving Multimodal Therapy

✍ Scribed by Shigenori Nagata; Yu-Fen Jin; Katsuhiko Yoshizato; Miki Tomoeda; Misa Song; Norishige Iizuka; Masanori Kitamura; Hidenori Takahashi; Hidetoshi Eguchi; Hiroaki Ohigashi; Osamu Ishikawa; Yasuhiko Tomita

Book ID: 111773085
Publisher: Springer
Year: 2009
Tongue: English
Weight: 365 KB
Volume: 16
Category: Article
ISSN: 1068-9265
DOI: 10.1245/s10434-009-0532-3

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## Abstract The epidermal growth factor receptor (EGFR) has previously been detected in the nucleus of cancer cells and primary tumors. We have reported that EGFR translocates from the plasma membrane to the nucleus. Accumulation of nuclear EGFR is linked to increased DNA synthesis and proliferatio