## Abstract Interleukin‐2 (IL‐2) treatment is currently used to enhance T cell‐mediated immune responses against tumors or in viral infections. At the same time, IL‐2 is essential for the peripheral homeostasis of CD4^+^CD25^+^Foxp3^+^ regulatory T cells (Treg). In our study, we show that IL‐2 is a
✦ LIBER ✦
CD4+Foxp3+ regulatory T cells suppress γδ T-cell effector functions in a model of T-cell-induced mucosal inflammation
✍ Scribed by Ekaterina Yurchenko; Megan K. Levings; Ciriaco A. Piccirillo
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 546 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0014-2980
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## Background: Cd4+cd25+ regulatory t cells (tr) can prevent or treat experimental murine colitis but little is known about their potential role in human inflammatory bowel disease (ibd). foxp3 is a transcription factor that plays a critical role in the development and function of cd4+cd25+ tr. the
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