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CD4(+)CD25highregulatory T cells increase with tumor stage in patients with gastric and esophageal cancers

✍ Scribed by Koji Kono; Hiromichi Kawaida; Akihiro Takahashi; Hidemitsu Sugai; Kosaku Mimura; Naoto Miyagawa; Hideo Omata; Hideki Fujii


Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
312 KB
Volume
55
Category
Article
ISSN
0340-7004

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CD4+CD25+ regulatory T cells in patients
✍ Tetsuro Sasada; Motohide Kimura; Yuka Yoshida; Michiyuki Kanai; Arimichi Takabay πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 191 KB

## Abstract ## BACKGROUND Active suppression by CD4^+^CD25^+^ regulatory T cells plays an important role in the down‐regulation of the response of T cells to foreign and self antigens. Experimental tumor models in mice revealed that regulatory T cells inhibit antitumor immune responses. The purpos