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Variations in the number of regulatory T cells (CD4+CD25+) in patients with breast cancer during Herceptin therapy

✍ Scribed by E. G. Slavina; A. I. Chertkova; T. N. Zabotina; I. P. Gan’shina; M. R. Lichinitser

Publisher
Springer US
Year
2006
Tongue
English
Weight
254 KB
Volume
141
Category
Article
ISSN
0007-4888

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CD4+CD25+ regulatory T cells in patients
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✍ Tetsuro Sasada; Motohide Kimura; Yuka Yoshida; Michiyuki Kanai; Arimichi Takabay 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 191 KB

## Abstract ## BACKGROUND Active suppression by CD4^+^CD25^+^ regulatory T cells plays an important role in the down‐regulation of the response of T cells to foreign and self antigens. Experimental tumor models in mice revealed that regulatory T cells inhibit antitumor immune responses. The purpos